The International Thermonuclear Experimental Reactor(ITER) poloidal field(PF) AC/DC converters are composed by thyristor-based phase controlled converter modules. As the core component of ITER PF AC/DC converter, the thyristor is very sensitive to over-voltage and damaged in microseconds, therefore, the transient over-voltage protection strategy is desperately essential to ensure the converter safety operation. In this paper, a nanosecond respond and high reliability protection strategy which combined by Metal Oxide Varistor(MOV) and external bypass is proposed to protect the ITER PF AC/DC converter from transient DC over-voltage. The MOV is designed to certify the fast respond in nanosecond. Moreover, a bidirectional BreakOver Diode(BOD) circuit board is designed to activate external bypass to ensure the reliability of the transient DC over-voltage protection strategy. The performance-testing platform is built to study its performance. The experiments on ITER PF AC/DC converter test facility are carried out. According to the experiment results, the external bypass is triggered by BOD board effectively and the load current is transferred to the external bypass in 2 us when BOD suffers from an over-voltage. The effectiveness of the proposed transient DC over-voltage protection strategy is verified.